Research Article
Renin-Angiotensin System Gene Variants and Type 2 Diabetes Mellitus: Influence of Angiotensinogen
Table 2
Demographic and clinical data of male participants.
| | Characteristics | Mean ± SD | value | | Control () | DM () |
| | Age (years) | 57.4 ± 6.8 | 58.13 ± 6.2 | 0.753a | | BMI (kg/m2) | 26.7 ± 4.1 | 27.2 ± 4.1 | 0.986a | | Waist circumference (cm) | 90.8 ± 11.1 | 95.3 ± 11.7 | 0.003a | | Waist-to-hip ratio | 0.90 ± 0.1 | 0.94 ± 0.1 | <0.0001 | | Systolic pressure (mmHg) | 131.30 ± 15.7 | 133.78 ± 14.9 | 0.112 | | Diastolic pressure (mmHg) | 79.11 ± 10.3 | 78.22 ± 9.0 | 0.676 | | Fasting blood glucose (mmol/L) | 5.29 ± 0.7 | 8.33 ± 2.8 | <0.0001 | | HbA1c (%) (mmol/mol) | 5.44 ± 0.5 (35.93 ± 5.6) | 8.65 ± 2.0 (70.98 ± 21.7) | <0.0001 | | Serum urea (mmol/L) | 5.28 ± 2.3 | 5.42 ± 1.6 | 0.101 | | Serum creatinine (mmol/L) | 91.70 ± 19.5 | 99.60 ± 23.5 | 0.022 | | Glomerular filtration rate (mL/min/1.72 m2) | 79.20 ± 19.2 | 75.40 ± 21.1 | 0.232a | | Triglyceride (mmol/L) | 2.35 ± 8.1 | 1.78 ± 1.0 | 0.276 | | Total cholesterol (mmol/L) | 5.38 ± 5.9 | 4.50 ± 1.2 | 0.005 | | HDL cholesterol (mmol/L) | 1.24 ± 0.4 | 1.98 ± 9.2 | 0.088 | | LDL cholesterol (mmol/L) | 2.94 ± 0.9 | 2.53 ± 0.9 | <0.0001 |
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values were obtained using independent -test and other comparisons used Mann-Whitney test.
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