Renin-Angiotensin System Gene Variants and Type 2 Diabetes Mellitus: Influence of Angiotensinogen

Table 3

Association of AGT SNPs with diabetes in the male gender.

AGT	Allele frequency		Unadjusted value	Adjusted value^a	OR^a (95% CI)
	Control	DM
rs699 (T/C)
T	0.12	0.21	1		Reference
C	0.88	0.79	0.017	0.007	0.47 (0.27–0.81)
TT			1		Reference
TC			0.815	0.803	0.80 (0.14–4.66)
CC			0.395	0.209	0.33 (0.60–1.85)
rs4762 (C/T)
C	0.84	0.90	1		Reference
T	0.16	0.10	0.048	0.042	0.54 (0.29–0.98)
CC			1		Reference
CT			0.076	0.065	0.53 (0.27–1.04)
TT			0.245	0.320	0.31 (0.03–3.14)
rs5051 (A/G)
A	0.88	0.80	1		Reference
G	0.12	0.20	0.032	0.017	1.94 (1.13–3.36)
AA			1		Reference
AG			0.022	0.026	2.09 (1.09–4.00)
GG			0.414	0.226	2.87 (0.52–15.75)

Adjusted for waist circumference, age, and BMI.