The Role of Hyperglycemia and Insulin Resistance in the Development and Progression of Pulmonary Arterial Hypertension

Table 1

Current clinical classification of pulmonary hypertension.

Group	Associated conditions
() Pulmonary arterial hypertension	Idiopathic, heritable, and connective tissue diseases, congenital heart diseases, drug and toxins, portal hypertension, and schistosomiasis
() Diseases affecting pulmonary; capillaries or pulmonary venules	Pulmonary venoocclusive disease or pulmonary capillary hemangiomatosis
() Pulmonary venous hypertension	Left ventricular systolic or diastolic dysfunction or left sided valvular heart disease
() PH due to lung disease or hypoxemia	Sleep disordered breathing, chronic altitude exposure, chronic obstructive lung disease, and interstitial lung disease
() Chronic thromboembolic pulmonary hypertension
() PH due to multifactorial mechanisms	Sarcoidosis, hematologic disorders, chronic renal failure, and glycogen storage disease