Research Article

Subclinical Alterations of Cardiac Mechanics Present Early in the Course of Pediatric Type 1 Diabetes Mellitus: A Prospective Blinded Speckle Tracking Stress Echocardiography Study

Table 1

Baseline clinical characteristics and hemodynamics of the study population.

Diabetes
()
Control
()
value

Age (years)11.5 ± 3.111.4 ± 2.9n.s.
Height (cm)153.0 ± 18.2154.1 ± 16.8n.s.
Weight (kg)46.9 ± 16.948.0 ± 16.3n.s.
Body surface (m2)1.4 ± 0.31.4 ± 0.3n.s.
Body mass index (kg/m2)19.3 ± 3.119.6 ± 3.5n.s.
Exercise routine (1: in school; 2: <3 times/week; 3: ≥3 times/week)1.7 ± 0.82.0 ± 0.7n.s.
Duration of disease (years)4 ± 3.5
HbA (%)8.3 ± 1.2
Rest
 Heart rate (beats/minute)84.4 ± 11.376.2 ± 9.40.001
 BP systolic (mmHg)105.7 ± 9.6105.8 ± 9.2n.s.
 BP diastolic (mmHg)58.5 ± 7.959.4 ± 9.2n.s.
Low stress level
 Heart rate (beats/minute)112.0 ± 9.3108.6 ± 12.8n.s.
 BP systolic (mmHg)122.3 ± 18.2120.2 ± 16.9n.s.
 BP diastolic (mmHg)65.2 ± 13.663.7 ± 11.0n.s.
 Level of resistance (W/kg body weight) 0.4 ± 0.30.5 ± 0.3n.s.
High stress level
 Heart rate (beats/minute)161.5 ± 13.1156.8 ± 17.5n.s.
 BP systolic (mmHg)148.1 ± 21.9140.1 ± 22.9n.s.
 BP diastolic (mmHg)74.9 ± 12.671.2 ± 13.8n.s.
 Level of resistance (W/kg body weight) 1.7 ± 0.41.8 ± 0.4n.s.

values calculated with the Man-Whitney test, level of significance = 0.05.