Identification of HNF4A Mutation p.T130I and HNF1A Mutations p.I27L and p.S487N in a Han Chinese Family with Early-Onset Maternally Inherited Type 2 Diabetes

Table 1

HeLa cells were transfected with a combination of different vectors.

HeLa	1	2	3	4
Empty pCDH-vector	−	++	+	+
HNF4A-WT vector	−	−	+	−
HNF4A-T130I vector	−	−	−	+
PGL-HNF1A reporter vector	+	+	+	+
TK	+	+	+	+

Note: 4 μg HNF4A-WT, HNF4A-T130I vector, or empty pCDH-vector (total of 8 μg), 3 μg reporter construct were transfected and 0.2 μg TK was used to control transfection efficiency.