Research Article

Exenatide Activates the APPL1-AMPK-PPARα Axis to Prevent Diabetic Cardiomyocyte Apoptosis

Table 4

Protein expression levels of APPL1, p-AMPK/T-AMPK, PPAR, GRP78, and NF-B.

ControlDDIDE

APPL10.75 ± 0.030.36 ± 0.030.36 ± 0.040.65 ± 0.02
p-AMPK/0.94 ± 0.020.58 ± 0.040.60 ± 0.030.78 ± 0.04
T-AMPK1.14 ± 0.131.06 ± 0.031.12 ± 0.121.05 ± 0.09
p-AMPK/T-AMPK0.83 ± 0.080.55 ± 0.030.55 ± 0.090.75 ± 0.04
PPARα1.89 ± 0.031.25 ± 0.151.27 ± 0.051.72 ± 0.05
GRP780.44 ± 0.040.77 ± 0.050.70 ± 0.050.34 ± 0.02
NF-B0.35 ± 0.051.39 ± 0.081.41 ± 0.080.58 ± 0.09

Compared with the D group, ; Compared with the DI group, .