Research Article
Exenatide Activates the APPL1-AMPK-PPARα Axis to Prevent Diabetic Cardiomyocyte Apoptosis
Table 4
Protein expression levels of APPL1, p-AMPK/T-AMPK, PPAR
, GRP78, and NF-
B.
| | Control | D | DI | DE |
| APPL1 | 0.75 ± 0.03 | 0.36 ± 0.03 | 0.36 ± 0.04 | 0.65 ± 0.02 | p-AMPK/ | 0.94 ± 0.02 | 0.58 ± 0.04 | 0.60 ± 0.03 | 0.78 ± 0.04 | T-AMPK | 1.14 ± 0.13 | 1.06 ± 0.03 | 1.12 ± 0.12 | 1.05 ± 0.09 | p-AMPK/T-AMPK | 0.83 ± 0.08 | 0.55 ± 0.03 | 0.55 ± 0.09 | 0.75 ± 0.04 | PPARα | 1.89 ± 0.03 | 1.25 ± 0.15 | 1.27 ± 0.05 | 1.72 ± 0.05 | GRP78 | 0.44 ± 0.04 | 0.77 ± 0.05 | 0.70 ± 0.05 | 0.34 ± 0.02 | NF-B | 0.35 ± 0.05 | 1.39 ± 0.08 | 1.41 ± 0.08 | 0.58 ± 0.09 |
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Compared with the D group, ; Compared with the DI group, .
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