Research Article
Sex Differences in the Renal Function Decline of Patients with Type 2 Diabetes
Table 2
The relationships between baseline variables and the annual eGFR change in males and females.
| | | Univariate analysis | Multivariable analysis | | | | value | | value |
| | Males | | | | | | DR (yes/no) | −0.264 | <0.001 | −0.161 | 0.019 | | Proteinuria (yes/no) | −0.243 | <0.001 | −0.139 | 0.041 | | Diabetes duration (years) | −0.158 | 0.017 | −0.097 | 0.142 | | HbA1c (% or mmol/mol) | −0.135 | 0.036 | −0.084 | 0.182 | | SBP (mmHg) | −0.136 | 0.032 | −0.065 | 0.301 | | LDL-cholesterol (mmol/L) | −0.006 | 0.920 | — | — | | Overweight (yes/no) | 0.062 | 0.332 | — | — | | Ever-smoker (yes/no) | −0.021 | 0.745 | — | — | | Females | | | | | | DR (yes/no) | −0.465 | <0.001 | −0.248 | 0.022 | | Proteinuria (yes/no) | −0.344 | <0.001 | −0.207 | 0.026 | | Diabetes duration (years) | −0.256 | 0.013 | −0.160 | 0.101 | | HbA1c (% or mmol/mol) | −0.377 | <0.001 | −0.191 | 0.049 | | SBP (mmHg) | −0.243 | 0.018 | −0.127 | 0.154 | | LDL-cholesterol (mmol/L) | −0.267 | 0.009 | −0.182 | 0.041 | | Overweight (yes/no) | 0.058 | 0.587 | — | — | | Ever smoker (yes/no) | 0.049 | 0.644 | — | — |
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Adjusted for baseline age.
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