Research Article
Par-4/NF-κB Mediates the Apoptosis of Islet β Cells Induced by Glucolipotoxicity
Table 2
The insulin secretion, Par-4 secretion, apoptosis rate, and protein expression of GRP78 and Par-4 of each group.
| | C | C + Par-4 | C − Par-4 | H | H + Par-4 | H − Par-4 |
| Insulin (mIU/L) | 6.67 ± 0.24 | 6.43 ± 0.30 | 6.65 ± 0.36 | 3.60 ± 0.20 | 2.29 ± 0.08 | 4.48 ± 0.26 | Par-4 (mg/L) | 70.05 ± 14.18 | 71.78 ± 19.38 | 67.60 ± 16.32 | 388.18 ± 18.43 | 766.22 ± 16.15 | 164.58 ± 16.63 | Apoptosis rate (%) | 2.88 ± 1.25 | 3.13 ± 1.55 | 2.13 ± 1.13 | 45.38 ± 7.91 | 62.75 ± 10.55 | 31.63 ± 6.00 | GRP78 | 0.14 ± 0.01 | 0.14 ± 0.04 | 0.15 ± 0.03 | 0.89 ± 0.05 | 1.18 ± 0.13 | 0.60 ± 0.10 | Par-4 | 0.81 ± 0.03 | 1.11 ± 0.03 | 0.63 ± 0.03 | 1.67 ± 0.10 | 2.22 ± 0.08 | 0.91 ± 0.04 |
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Compared with H group; . Compared with H − Par-4 group; . Compared with H + Par-4 group; .
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