CCL2 Serum Levels and Adiposity Are Associated with the Polymorphic Phenotypes -2518A on CCL2 and 64ILE on CCR2 in a Mexican Population with Insulin Resistance
Table 1
Anthropometric characteristics and metabolic markers in individuals included in the study.
Measurement
Study group
Individuals without IR
Individuals with IR
(%)
270 (68)
110 (32)
Age (years)
35 ± 14
34 ± 14
NS
Height (cm)
163.8 ± 5.7
165.7 ± 1.1
NS
Weight (kg)
68.7 ± 13.2
79.4 ± 16.3
<
BMI (kg/m2)
24.9 (22.6–28.9)
28.6 (24.4–31.7)
<
Body fat mass (kg)
20.1 ± 9.2
25.9 ± 11.3
<
Total body fat mass (%)
28.8 ± 9.4
32.80 ± 9.2
<
BFR (kg/m2)
7.03 (5.24–9.40)
9.40 (6.37–12.20)
Waist circumference (cm)
86.5 (77.1–93.1)
95.0 (83–103)
<
Hip circumference (cm)
99.5 (95–105.9)
104 (99–110)
WHR
0.854 (0.68–1.17)
0.866 (0.70–1.28)
NS
WHtR
0.533 ± 0.076
0.568 ± 0.085
<
Glucose (mg/dL)
89 ± 10
98 ± 18
<
Insulin (µUI/mL)
8.6 ± 3.5
35.2 ± 32.5
<
HOMA-IR
1.86 (1.34–2.58)
6.05 (4.40–9.03)
<
Triglycerides (mg/dL)
134 ± 83
162 ± 95
Total cholesterol (mg/dL)
184 ± 40
185 ± 34
NS
HDLc (mg/dL)
39.5 ± 15.1
37.6 ± 14.9
NS
LDLc (mg/dL)
111 ± 36
110 ± 31
NS
VLDLc (mg/dL)
26 ± 16
32 ± 19
Apo-A1 (mg/dL)
114 ± 25
117 ± 27
NS
Apo-B (mg/dL)
111 ± 32
117 ± 32
NS
. Data are presented as mean ± standard deviation and median (25–75 percentiles). Student’s -test and Mann-Whitney test with significantly, comparing the groups: individuals with IR versus individuals without IR. IR: insulin resistance; BMI: body mass index; WHR: waist to hip ratio; WHtR: waist to height ratio; BFR: body fat ratio; HOMA-IR: homeostasis model assessment-insulin resistance; HDLc, LDLc, and VLDLc: high, low, and very low density lipoprotein cholesterol, respectively; Apo: apolipoprotein.
