Reversibility of β-Cell-Specific Transcript Factors Expression by Long-Term Caloric Restriction in db/db Mouse

Figure 6

Real-time PCR analysis of GLP-1 in the colonic tissue (a) and GLP-1R and PKC (b) in the islets in the db/m-F, db/db-F, and db/db-R mice. (c) Immunofluorescence analysis of PKCζ expression levels in islets from db/m-F, db/db-F, and db/db-R mice., . The data shown represent three independent experiments. db/db-F and db/db mice given free access to regular chow; db/db-R and db/db mice receiving restricted food supply; db/m-F and db/m mice given free access to regular chow. Scale bars: 25 μm.

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