Development of Diagnostic Biomarkers for Detecting Diabetic Retinopathy at Early Stages Using Quantitative Proteomics

Figure 2

The reproducibility of the 3 independent MRM analyses. Before performing the SQ-MRM analysis, we first determined the reproducibility in 3 independent experiments using pooled plasma samples; representative results of 15 proteins are shown. The reproducibility testing showed that APLP2, FN1, ITIH2, and SERPINF1 had higher CV values (19%, 14%, 18%, and 13%, resp.), while the other proteins had lower CV values.