Development of Diagnostic Biomarkers for Detecting Diabetic Retinopathy at Early Stages Using Quantitative Proteomics

Figure 5

The detection of noise signals for heavy peptides in the pooled plasma. Noise signals of heavy peptides were assessed by analyzing TEST sample #2, which was composed of only endogenous light peptides (pooled plasma, 1 μg without heavy peptide). A range of noise signals was detected for APLP2, B3GNT1, CD14, and GSN, while a noise signal was barely detected for the other proteins.