Antidiabetic Effect of Young and Old Ethanolic Leaf Extracts of Vernonia amygdalina: A Comparative Study

Figure 3

Photomicrograph of spleen sections. (a) Normal control: normal architecture of spleen with presence of marginal zone between red and white pulp. (b) Negative control: hypercellularity and haemosiderosis with loss of marginal zone and dilatation of blood vessels. (c) Positive control: it shows no sign of hypercellularity or haemosiderosis. Sections (d) (10 mg/kg YL), (e) (10 mg/kg OL), (f) (30 mg/kg YL), (g) (30 mg/kg OL), (h) (300 mg/kg YL), and (i) (300 mg/kg OL) all show evidence of hypercellularity of resident cells and absence of haemosiderosis (H&E stain 100x). Bar = 20 μm.

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