Antidiabetic Effect of Young and Old Ethanolic Leaf Extracts of Vernonia amygdalina: A Comparative Study
Table 4
Effect of young and old ethanolic leaf extracts of V. amygdalina on haematological parameters.
Parameters
Normal control
Negative control
Positive control
10 mg/kg YL
30 mg/kg YL
300 mg/kg YL
10 mg/kg OL
30 mg/kg OL
300 mg/kg OL
RBC (M/)
8.20 ± 0.18
6.50 ± 0.03
8.0 ± 0.64
7.76 ± 0.30
8.61 ± 0.16
7.20 ± 0.12
8.26 ± 0.16
7.38 ± 1.12
7.19 ± 4.02
Hb (g/dL)
16.22 ± 0.25
13.04 ± 1.05
14.7 ± 1.03
14.05 ± 0.97
15.20 ± 0.30
13.53 ± 0.14
14.11 ± 0.19
13.7 ± 2.11
14.26 ± 0.21
HCT (%)
48.40 ± 0.23
37.2 ± 2.01
42.8 ± 3.54
43.73 ± 0.14
49.01 ± 1.10
38.7 ± 0.38
45.4 ± 0.86
39.3 ± 0.45
391.7 ± 0.24
MCV (fL)
53.04 ± 0.62
53.01 ± 3.02
53 ± 2.07
55.01 ± 0.40
53.11 ± 0.13
54.03 ± 0.12
55.12 ± 0.45
53.4 ± 2.42
56.29 ± 0.10
MCH (pg)
17.82 ± 0.11
18.6 ± 0.12
18.4 ± 0.54
16.50 ± 0.13
18.11 ± 0.30
18.30 ± 0.14
14.08 ± 0.26
17.2 ± 0.22
18.06 ± 0.47
MCHC (g/dL)
33.40 ± 0.43
35.9 ± 1.21
34.4 ± 0.34
29.20 ± 0.24
34.09 ± 0.21
35.40 ± 3.01
29.90 ± 0.51
32.3 ± 0.21
37.22 ± 0.13
LYM (%)
55.90 ± 0.09
52.5 ± 0.32
46.9 ± 4.03
51.14 ± 6.12
48.26 ± 0.36
47.1 ± 0.33
52.40 ± 0.11
44.9 ± 0.05
57.12 ± 0.09
MON (%)
1.46 ± 0.14
14.21 ± 0.18
1.60 ± 0.03
2.60 ± 0.11
2.12 ± 0.53
8.20 ± 2.13
5.10 ± 0.16
4.21 ± 2.03
6.10 ± 2.31
NEU (%)
39.10 ± 3.03
30.20 ± 1.12
40.1 ± 0.25
33.12 ± 2.10
40.80 ± 0.17
33.40 ± 0.05
31.30 ± 0.33
35.12 ± 0.41
37.31 ± 5.10
Values are expressed as mean ± SEM (); was considered statistically significant. = statistical difference between treated groups and negative control. Red blood cells, RBC; haemoglobin, Hb; haematocrit, HCT; mean corpuscular volume, MCV; mean corpuscular haemoglobin, MCH; mean corpuscular haemoglobin concentration, MCHC; monocytes, MON; neutrophils, NEU; and lymphocytes, LYM.
