Brain Activation and Psychomotor Speed in Middle-Aged Patients with Type 1 Diabetes: Relationships with Hyperglycemia and Brain Small Vessel Disease

Table 2

Age-adjusted associations between HbA1c months and DSST response time while in the scanner.

	Age-adjusted betas (standard errors), value
Model 1	0.249 (0.075),
Model 2, adjusted for WMH (Fazekas)	0.261 (0.074),
Model 3, adjusted for distal symmetric polyneuropathy	0.221 (0.075),
Model 4, adjusted for overt nephropathy	0.265 (0.088),
Model 5, adjusted for proliferative retinopathy	0.171 (0.078),

Adjusted for interval of time between date of documentation of that complication (2004–2006) and date of MRI (2010–2013).