Brain Activation and Psychomotor Speed in Middle-Aged Patients with Type 1 Diabetes: Relationships with Hyperglycemia and Brain Small Vessel Disease

Table 4

Regions with functional activation that were positively correlated with hemoglobin A1c months. No significant voxels were negatively correlated with hemoglobin A1c months.

Regions	Cluster size	Peak -Score (df = 84)	Montreal Neurological Institute coordinate for Peak -Score
Right dorsal cingulate gyrus	274	3.58	26, 2, 34
Right precentral gyrus	267	3.65	50, −8, 31^1
Right inferior frontal gyrus, pars orbitalis	134	3.55	50, 14, 7

This table reports the spatial distribution of the association of hemoglobin A1c months with the mean group activation (obtained from the DSST > control condition contrast), including the size of cluster, the maximum statistic for the cluster, and the location of the maximum statistic in Montreal Neurological Institute coordinates. The corrected alpha is the probability of false positive detection based on the combination of individual voxel probability thresholding and minimum cluster size thresholding.
¹This cluster extended caudally to the right postcentral gyrus.