Insulin Resistance Predicts Atherogenic Lipoprotein Profile in Nondiabetic Subjects
Table 2
Biochemical profile of the subject according presence of insulin resistance.
Variables
Total ()
Non-IR group ()
IR group ()
TC (mmol/L)
5.38 (1.01)
5.43 (0.91)
5.35 (1.06)
0.591
HDL-C (mmol/L)
0.98 (0.28)
1.09 (0.26)
0.93 (0.28)
0.001
LDL-C (mmol/L)
3.67 (0.91)
3.72 (0.80)
3.62 (1.04)
0.495
TAG (mmol/L)
1.37 (1.03; 1.99)
1.15 (0.97; 1.50)
1.52 (1.14; 2.16)
<0.001
Glucose (mmol/L)
5.33 (8; 5.7)
5.1 (4.8; 5.3)
5.4 (5.1; 5.8)
<0.001
Insulin (μU/mL)
17.0 (7.0)
12.0 (3.0)
20.0 (7.0)
<0.001
HOMA-IR
4.2 (1.9)
2.8 (0.7)
5.0 (2.0)
<0.001
TAG/HDL-C
1.5 (1.0; 2.3)
1.9 (0.8; 1.5)
1.6 (1.2; 2.6)
<0.001
Non-HDL-C (mmol/L)
4.42 (0.95)
4.38 (0.91)
4.42 (0.98)
0.686
APO AI (g/L)
1.33 (0.27)
1.42 (0.24)
1.29 (0.28)
0.001
APO B (g/L)
1.05 (0.23)
1.04 (0.23)
1.05 (0.23)
0.752
LDL size (Å)
270.0 (267.0; 272.0)
271.0 (269.0; 272.0)
270.0 (265.0; 272.0)
0.045
Phenotype A (n, %)
125.0 (69.0)
53.0 (83.0)
72.0 (62.0)
0.003
Data presented as mean (standard deviation) and median (p25-p75). Comparative analysis was performed by Student’s t-tests or Mann–Whitney U test (). TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; TAG: triacylglycerol; TAG/HDL-C: ratio between TAG and HDL-C; APO AI: apolipoprotein AI; APO B: apolipoprotein B; non-IR group: individuals without insulin resistance; IR group: individuals with insulin resistance.
