Antidiabetic Effect of Brain-Derived Neurotrophic Factor and Its Association with Inflammation in Type 2 Diabetes Mellitus

Figure 1

Brain-derived neurotrophic factor (BDNF) and its role on glucose haemostasis and potential relation with inflammation and type 2 diabetes mellitus (T2DM). MC₄-R: melanocortin 4 receptor; TrkB: tropomyosin receptor kinase B; IL-6: interleukin 6; TNF-α: tumor necrosis factor alpha; CRP: c-reactive protein; PBMC: peripheral blood mononuclear cell.