Renoprotective Effect of the Shen-Yan-Fang-Shuai Formula by Inhibiting TNF-α/NF-κB Signaling Pathway in Diabetic Rats

Figure 6

SYFSF serum inhibited fibrotic cytokine expression in high-glucose-treated mesangial cells. SYFSF inhibited the expression of TGF-β1, collagen IV, and fibronectin in high-glucose-treated mesangial cells. HG + S represents the mesangial cells treated with high-glucose medium and serum from rats treated with SYFSF. HG + I represents the mesangial cells treated with high-glucose medium and serum from rats treated with irbesartan.