Risk of Type 2 Diabetes Mellitus following Gestational Diabetes Pregnancy in Women with Polycystic Ovary Syndrome
Table 2
Baseline characteristics and incident diabetes mellitus (DM) in women with polycystic ovary syndrome (PCOS) and gestational diabetes mellitus (GDM) pregnancy.
186 PCOS women with GDM by subsequent DM status
Adjusted relative rate of DM following GDM pregnancy
No diabetes
Diabetes
value
Adjusted hazard ratio
95% confidence interval
Age, years (mean ± standard deviation)
32.9 ± 4.1
33.3 ± 3.4
0.57
1.01
0.91–1.12
Race/ethnicity
White
31.1%
32.0%
0.44
Referent
Black
3.1%
0.0%
—§
Hispanic
23.0%
40.0%
1.38§
0.51–3.74
Asian
39.8%
28.0%
1.96
0.55–6.94
Other
3.1%
0.0%
—§
Prepregnancy BMI (kg/m2)
31.6 ± 7.6
37.5 ± 7.1
<0.01
1.09
1.03–1.15
Family history of diabetes
62.7%
80.0%
0.12
1.59
0.56–4.46
Preconception metformin†
34.2%
48.0%
0.18
0.91
0.39–2.11
Pharmacologic treatment for GDM
23.6%
60.0%
<0.01
4.10
1.75–9.57
One woman with no follow-up after delivery and 5 women with incident DM during the first year after delivery were not included. †Administered within 3 months of conception to assist in achieving ovulation. §Women of other () or Black () race were included with the 47 women of Hispanic ethnicity for these analyses.
