Association between STK11 Gene Polymorphisms and Coronary Artery Disease in Type 2 Diabetes in Han Population in China
Table 3
Association between CAD and SNPs at STK11 locus in different genetic model.
SNPs
Genotype
CAD
Control
OR
95% CI
95%
rs3764640
TT
98 (40.0)
53 (39.0)
1.155
0.660–2.020
0.665
1.019
0.445–2.331
0.964
GG+GT
147 (60.0)
83 (61.0)
1
1
rs6510599
CC+CT
233 (85.3)
116 (83.5)
1.055
0.680–1.603
0.913
1.104
0.840–1.452
0.477
TT
40 (14.7)
23 (16.5)
1
1
rs35369365
GG+GA
160 (62.5)
83 (55.0)
1.365
0.908–2.054
0.144
1.275
0.981–1.656
0.069
AA
96 (37.5)
68 (45.0)
1
1
rs9282860
CC
204 (73.6)
105 (72.9)
1.038
0.659–1.635
0.908
1.002
0.965–1.040
0.926
TT+TC
73 (26.4)
39 (27.1)
1
1
rs12977689
AA+AC
161 (61.5)
71 (50.4)
1.572
1.039–2.376
0.035
1.184
1.036–1.353
0.013
CC
101 (38.5)
70 (49.6)
1
, 95% , : After adjustment for age, sex, duration of diabetes and hypertension, BMI, smoking, and plasma lipid status. refers to the significant difference between the CAD and control groups.
