Diabetes Is Associated with Increased Autoreactivity of Mannan-Binding Lectin

Figure 2

Blood glucose and weight gain of diabetic and nondiabetic control MBL/DKO and WT C57BL/6J mice. (a and b) Blood glucose and weight measurements for diabetic mice destined to be treated with rMBL AF680 (), diabetic mice destined to be treated with PBS (), control mice destined to be treated with rMBL AF680 (), and control mice destined to be treated with PBS (). (c and d). Comparison of the development of diabetes according to rising blood glucose levels and weight gain between diabetic () and control () C57BL/6J MBL/DKO mice and diabetic () and control () C57BL/6J WT mice. Statistical tests are given in the figure when significant, and comparisons are made between STZ treated and untreated groups at study end (). Values are given in mean (dots) with SD (whiskers).

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