Review Article
MicroRNAs-Mediated Regulation of Skeletal Muscle GLUT4 Expression and Translocation in Insulin Resistance
Table 1
Insulin resistance-induced regulation of miRNAs related to proteins of the GLUT4 translocation machinery in skeletal muscle.
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nomenclature of miRNAs is in accordance with the “miRBase Sequence Database-Release 21.” names are based on HGNC (HUGO Gene Nomenclature Committee), and despite some date being related to mouse/rat gene, description was related to human gene (capital letters). IR, insulin resistance/resistant; T2DM, type 2 diabetes mellitus; GK, Goto-Kakizaki; INSR, insulin receptor; IRS1, insulin receptor substrate 1; IRS2, insulin receptor substrate 2; MAPK14, mitogen-activated protein kinase 14; AKT2, AKT serine/threonine kinase 2; PI3KR1, phosphoinositide-3-kinase regulatory subunit 1; MTOR, mechanistic target of rapamycin; RPS6KB1, ribosomal protein S6 kinase B1; RAC1, ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1). |