Research Article

Metformin Improves Epithelial-to-Mesenchymal Transition Induced by TGF-β1 in Renal Tubular Epithelial NRK-52E Cells via Inhibiting Egr-1

Figure 2

Egr-1 induced by TGF-β1 in NRK-52E cells. NRK-52E cells were treated with 10 ng/ml TGF-β1 for the indicated times. (a–c) The mRNA (a) and protein (b, c) expressions of Egr-1 were significantly upregulated at 30 min and 2 h, respectively. Values are shown as mean ± SD. for each group. , , and versus 0 h group.
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