Metformin Improves Epithelial-to-Mesenchymal Transition Induced by TGF-<i>β</i>1 in Renal Tubular Epithelial NRK-52E Cells via Inhibiting Egr-1

<div>Metformin inhibiting the expression of Egr-1 induced by TGF-<i>β</i>1 in NRK-52E cells. NRK-52E cells were treated by 10 ng/ml TGF-<i>β</i>1 with or without metformin. (a) The mRNA expressions of Egr-1 induced by TGF-<i>β</i>1 was suppressed by metformin. (b, c) The protein expression of Egr-1 induced by TGF-<i>β</i>1 was inhibited by metformin. 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Journal of Diabetes Research

fig5

Figure 5

Figure 5: Metformin Improves Epithelial-to-Mesenchymal Transition Induced by TGF-<i>β</i>1 in Renal Tubular Epithelial NRK-52E Cells via Inhibiting Egr-1 

Journal of Diabetes Research

Metformin Improves Epithelial-to-Mesenchymal Transition Induced by TGF-β1 in Renal Tubular Epithelial NRK-52E Cells via Inhibiting Egr-1

Figure 5