The U-Shaped Association between Bilirubin and Diabetic Retinopathy Risk: A Five-Year Cohort Based on 5323 Male Diabetic Patients

Table 2

Incidence of DR according to baseline TBiL quintiles and follow-up TBiL changes.

DR	Quintiles of baseline TBiL(μmol/L)					Follow-up TBiL changes (μmol/L)			Total
	Q1 (≤9.20)	Q2 (9.20–12.60)	Q3 (12.60–13.80)	Q4 (13.80–16.50)	Q5 (≥16.50)	≤−2	−2 to 2	≥2
Number of incident cases	61	57	40	51	60	115	105	49	269
Incidence (%)	5.6 (4.3–7.0)	5.4 (4.0–6.8)	3.4 (2.4–4.5)	5.2 (3.8–6.2)	5.7 (4.3–7.1)	6.3 (5.2–7.5)	4.9 (4.0–5.9)	3.7 (2.7–4.8)	5.1 (4.5–5.6)
Total person-years	4399	4302	4638	3981	4267	7443	8692	5451	21,586
Incidence density (per 100 person-years)	1.4 (1.1–1.8)	1.3 (1.0-1.7)	0.9 (0.6–1.2)	1.3 (1.0-1.7)	1.4 (1.1–1.8)	1.5 (1.3–1.9)	1.2 (1.0-1.5)	0.9 (0.7–1.2)	1.2 (1.1–1.4)