Insulin Modulates Paracoccidioides brasiliensis-Induced Inflammation by Restoring the Populations of NK Cells, Dendritic Cells, and B Lymphocytes in Lungs

Figure 5

Cytokine and chemokine profiles in organ homogenates. Mice were rendered diabetic via injection of alloxan (60 mg/kg i.v.) and infected with P. brasiliensis (1 × 10⁶ cells i.t.). Tissue samples were obtained 55 days after alloxan injection and 45 days after the incubation period. Five animals were used for each group. Values are the means ± SEM. ; ; . (a–d) Cytokine analysis in lung homogenates; (e) CINC-1 concentration in the liver; (f) CINC-1 concentration in the spleen.

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