Research Article

Administration of RAS Inhibitor before the Onset of Diabetic Nephropathy Counteracts the Adverse Effect of Chronic Hyperglycemia and Reduces the Augmentation of Urinary Albumin Excretion: A Retrospective Clinical Study

Table 2

Association between the alteration of urinary albumin excretion and various clinical parameters: multivariate analysis.

Control groupRAS inhibitor group

HbA1c, annual mean7.574<0.005āˆ’1.749n.s.
Age, baseline0.208n.s.0.171n.s.
Systolic BP, annual meanāˆ’0.021n.s.0.165n.s.
Gender0.533n.s.1.017n.s.
eGFR, baseline0.019n.s.0.142n.s.

Abbreviations: n.s., not significant; BP, blood pressure; RAS, renin-angiotensin system.