Roles of Identified Long Noncoding RNA in Diabetic Nephropathy

Figure 1

The roles of lncRNAs in diabetic nephropathy. Dysregulation of upregulated lncRNA (LncPVT1, MALAT1, Gm4419, GM5524, NR_033515, Erbb4-IR, ASncmtRNA-2, and Lnc-MGC) and downregulated lncRNA (TUG1, MIAT, CASC2, ENSMUST00000147869, 1700020I14Rik, CYP4B1-PS1-001, Gm15645, and LINC01619) involved in ECM maintenance and regulation of inflammation and podocyte damage, as described in the text. Red arrows indicate the damaging function of lncRNA upregulated in DN, and blue arrows indicate the protective functions of lncRNA downregulated in DN.