Clinical Study

Effects of Highly Absorbable Curcumin in Patients with Impaired Glucose Tolerance and Non-Insulin-Dependent Diabetes Mellitus

Table 1

Baseline characteristics of the participants in each group.

PlaceboTheracurmin® value

Sex (M/F)13/49/60.450
Age (years)0.857
Antihypertensive drug (% of total)88.286.7>0.999
α-Glucosidase inhibitor (% of total)23.513.30.658
DPP-4inhibitor (% of total)11.813.3>0.999
Sulfonylurea (% of total)013.30.212
Biguanide (% of total)23.513.30.659
Glinide (% of total)06.70.469
Thiazolidinediones (% of total)5.90>0.999
BMI (kg/m2)0.951
SBP (mmHg)0.474
DBP (mmHg)0.901
HbA1c (%)6.1 [6.0, 6.7]6.1 [6.0, 6.3]0.775
BS (mg/dL)110.0 [99.5, 160.5]109.5 [100.0, 145.8]0.766
TG (mg/dL)159 [88, 197]144 [86, 177]0.521
LDL-C (mg/dL)0.860
HDL-C (mg/dL)0.063
UA (mg/dL)0.366
γ-GTP (IU/L)29.0 [21.5, 49.5]32.0 [21.0, 57.0]0.910
Cre (mg/dL)0.8 [0.8, 0.9]0.8 [0.6, 0.9]0.265
SAA-LDL (μg/mL)5.0 [4.8, 8.0]5.0 [4.0, 7.0]0.686
AT-LDL (μg/mL)1.3 [1.0, 1.4]1.1 [1.0, 1.3]0.823
Adiponectin (μg/mL)0.528
Leptin (ng/mL)5.1 [2.3, 7.0]4.7 [2.1, 15.4]0.865
hs-CRP (mg/dL)0.6 [0.4, 1.8]0.6 [0.2, 1.1]0.560
CCr (mL/min/1.73m2)0.857

Data are presented as the , or median [minimum, maximum], or number of patients. M/F: male/female; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; HbA1c: hemoglobin A1c; BS: blood sugar; TG: triglyceride; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; UA: uric acid; γ-GTP: γ-glutamyl transpeptidase; Cre: creatinine; SAA-LDL: serum amyloid A-LDL; AT-LDL: a1-antitrypsin-LDL; hs-CRP: high-sensitivity C-reactive protein; CCr: creatinine clearance.