Research Article
Inhibition of HDAC3 Ameliorates Cerebral Ischemia Reperfusion Injury in Diabetic Mice In Vivo and In Vitro
Figure 1
Inhibition of HDAC3 played protective effects against cerebral I/R injury. Brain tissues were collected for determination of cerebral infarct volume by TTC staining (a, b) and observation of pathological changes by H&E staining (c) in each group. PC12 cells were collected for assessment of cell viability assessed by CCK-8 (d) and cytotoxicity by lactate dehydrogenase (LDH) release (e) in each group. All values are presented as , /group. versus the DS group, versus the DIR group, versus the HG group, and versus the HH/R group.
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