The APOE3-Leiden Heterozygous Glucokinase Knockout Mouse as Novel Translational Disease Model for Type 2 Diabetes, Dyslipidemia, and Diabetic Atherosclerosis

Figure 6

Mild matrix expansion and vacuolized tubuli in all phenotypes. Presence of matrix expansion (a), nephrin score (b), and vacuolized tubuli (c) was scored in a range of 0–5. Significance of differences was calculated parametrically using a one-way ANOVA with Dunnett’s post hoc test. Data are presented as means ± SD (–10 per group).

(a)

(b)

(c)