Research Article

Development of AIDA v4.3b Diabetes Simulator: Technical Upgrade to Support Incorporation of Lispro, Aspart, and Glargine Insulin Analogues

Figure 8

Prototype simulation using the superposition principle to calculate a plasma insulin profile based on exogenous insulin injections and estimated basal endogenous insulin secretion in a type 2 diabetic patient who takes 6 units of short-acting (regular) insulin and 12 units of intermediate-acting (NPH type) insulin in the morning with a further 4 units of short-acting (regular) insulin and 8 units of intermediate-acting (NPH type) insulin in the evening. The estimated basal endogenous insulin secretion is shown by the light blue (cyan) line—and the overall plasma insulin profile is superimposed.
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