Journal of Environmental and Public Health
Volume 2010 (2010), Article ID 463926, 5 pages
doi:10.1155/2010/463926
Clinical Study

A Cluster of Legionnaires' Disease and Associated Pontiac Fever Morbidity in Office Workers, Dublin, June-July 2008

M. Ward,1 M. Boland,1 N. Nicolay,2,3 H. Murphy,1 J. McElhiney,1 C. Collins,4 M. Lynch,4 M. McCarthy,5 and J. O' Donnell2

1Department of Public Health, Health Services Executive, Dublin, Ireland
2Health Protection Surveillance Centre (HPSC), Dublin, Ireland
3European Programme for Intervention Epidemiology Training (EPIET), Dublin, Ireland
4Mater Misericordiae University Hospital, Dublin, Ireland
5Environmental Health Services, Health Services Executive, Dublin, Ireland

Received 15 October 2009; Revised 9 February 2010; Accepted 15 February 2010

Academic Editor: Gary M. Marsh

Copyright © 2010 M. Ward et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. B. Diederen, “Legionella species and Legionnaires' disease,” Journal of Infection, vol. 56, pp. 1–12, 2008.
  2. National Guidelines for the control of Legionellosis in Ireland, “Report of Legionnaires' disease subcommittee of the scientific advisory committee,” Health Protection Surveillance Centre, Dublin, Ireland, September 2009.
  3. J. A. Cayla, R. Maldonado, J. Gonzalez, et al., “A small outbreak of Legionnaires' disease in a cargo ship under repair,” European Respiratory Journal, vol. 17, no. 6, pp. 1322–1327, 2001. View at Publisher · View at Google Scholar · View at Scopus
  4. G. J. Sonder, J. A. van den Hoek, L. P. Bovée, et al., “Changes in prevention and outbreak management of Legionnaires disease in the Netherlands between two large outbreaks in 1999 and 2006,” Eurosurveillance, vol. 13, no. 38, pp. 1–5, 2008. View at Scopus
  5. N. Nicolay, M. Boland, M. Ward, et al., “Investigation of Pontiac like illness in office workers during an outbreak of Legionnaires' disease, 2008,” Epidemiology and Infection, pp. 1–7, 2010. View at Publisher · View at Google Scholar · View at PubMed
  6. K. D. Ricketts, C. Joseph, J. Lee, and G. Wewalka, “Survey on legislation regarding wet cooling systems in European countries,” Eurosurveillance, vol. 13, no. 38, 2008.
  7. C. H. Heath, D. I. Grove, and D. F. M. Looke, “Delay in appropriate therapy of Legionella pneumonia associated with increased mortality,” European Journal of Clinical Microbiology and Infectious Diseases, vol. 15, no. 4, pp. 286–290, 1996. View at Publisher · View at Google Scholar · View at Scopus
  8. C. Joseph, “New outbreak of legionnaires disease in the United Kingdom,” British Medical Journal, vol. 325, no. 7360, pp. 347–348, 2002. View at Scopus
  9. K. Lettinga, A. Verbon, G.-J. Weverling, et al., “Legionnaires' disease at a Dutch flower show: prognostic factors and impact of therapy,” Emerging Infectious Diseases, vol. 8, no. 12, pp. 1448–1454, 2002. View at Scopus
  10. K. E. Templeton, S. A. Scheltinga, P. Sillekens, et al., “Development and clinical evaluation of an internally controlled, single-tube multiplex real-time PCR assay for detection of Legionella pneumophila and other Legionella species,” Journal of Clinical Microbiology, vol. 41, no. 9, pp. 4016–4021, 2003. View at Publisher · View at Google Scholar · View at Scopus
  11. D. F. Yaradou, S. Hallier-Soulier, S. Moreau, et al., “Integrated real-time PCR for detection and monitoring of Legionella pneumophila in water systems,” Applied and Environmental Microbiology, vol. 73, no. 5, pp. 1452–1456, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  12. N. Wellinghausen, C. Frost, and R. Marre, “Detection of legionellas in hospital water samples by quantitative real-time light cycler PCR,” Applied and Environmental Microbiology, vol. 67, no. 9, pp. 3985–3993, 2001. View at Publisher · View at Google Scholar · View at Scopus
  13. A. Frej and B. Anne, Green Office Buildings: A Practical Guide to Development, ULI—The Urban Land Institute, Washington, DC, USA, 2005.
  14. P. H. Appleby, “ABC of work related disorders: building related illnesses,” British Medical Journal, vol. 313, no. 7058, pp. 674–677, 1996.
  15. T. F. Jones, R. F. Benson, E. W. Brown, J. R. Rowland, S. C. Crosier, and W. Schaffner, “Epidemiologic investigations of a restaurant associated outbreak of pontiac fever,” Clinical Infectious Diseases, vol. 37, no. 10, pp. 1292–1297, 2003. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  16. P. Tossa, M. Deloge-Abarkan, D. Zmirou-Navier, P. Hartemann, and L. Mathieu, “Pontiac fever: an operational definition for epidemiological studies,” BMC Public Health, vol. 6, article 112, 2006. View at Publisher · View at Google Scholar · View at PubMed
  17. H. M. Gotz, A. Tegnell, B. De Jong, et al., “A whirlpool associated outbreak of pontiac fever at a hotel in Northern Sweden,” Epidemiology and Infection, vol. 126, no. 2, pp. 241–247, 2001. View at Publisher · View at Google Scholar · View at Scopus
  18. L. J. Burnsed, L. A. Hicks, L. M. K. Smithee, et al., “A large, travel-associated outbreak of legionellosis among hotel guests: utility of the urine antigen assay in confirming pontiac fever,” Clinical Infectious Diseases, vol. 44, no. 2, pp. 222–228, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  19. P. H. Edelstein, “Urine antigen tests positive for pontiac fever: implications for diagnosis and pathogenesis,” Clinical Infectious Diseases, vol. 44, no. 2, pp. 229–231, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus