The LINA Study: Higher Sensitivity of Infant Compared to Maternal Eosinophil/Basophil Progenitors to Indoor Chemical Exposures

Table 3

Association between indoor chemical exposures and the number of IL-3-, IL-5-, or GM-CSF-stimulated eosinophil/basophil (Eo/B) colony forming units (CFUs) of two-year-old children and their mothers. Data are shown as median and interquartile range (IQR); analyses were performed using Mann-Whitney test; values < 0.05 are considered to be significant and printed in bold.

Indoor exposures	Exposure to ETS in dwelling			Usage of disinfectants in the household
	Yes	No		Yes	No
Eo/B CFUs	Median (IQR)			Median (IQR)
Mother
IL-3	18.8 (5.0–55.5)	8.5 (3.8–17.0)	0.116	10.5 (4.0–16.5)	7.8 (4.0–17.5)	0.790
IL-5				0.5 (0.3–1.3)	1.0 (0.5–1.5)	0.597
GM-CSF				7.0 (5.5–7.0)	4.8 (1.0–5.5)	0.312
Child
IL-3	23.0 (9.5–32.0)	8.0 (3.5–14.0)	0.010	9.8 (4.8–19.8)	6.0 (3.0–12.5)	0.067
IL-5	1.0 (0.5–4.5)	0.5 (0–1.5)	0.100	0.5 (0–1.8)	0.5 (0–1.5)	0.930
GM-CSF	12.0 (3.0–16.0)	2.5 (1.0–6.5)	0.014	3.8 (2.0–12.3)	1.8 (1.0–5.5)	0.031

Reduced number of cases; see Table A.1 of the Supplementary Data.
ETS: environmental tobacco smoke.