Research Article
Tissue Expression of Low and High Molecular Weight Cytokeratins in Lung Carcinoma Sections: Its Correlation with Some Clinic-Pathological Features
Table 1
Clinic-pathological characteristics.
| | Features | NSCLC () | SCLC () | value | | Number of cases (%) | Number of cases (%) |
| | Gender | | | | | Female | 15 (28.8) | 6 (37.5) | 0.5460 | | Male | 37 (71.2) | 10 (62.5) | | Age | | | | | <60 | 37 (71.2) | 13 (81.2) | 0.5294 | | ≥60 | 15 (28.8) | 3 (18.8) | | Tumor size (cm) | | | | | <3 | 12 (23.1) | 7 (43.7) | 0.1227 | | ≥3 | 40 (76.9) | 9 (56.3) | | Tumor stage | | | | | Limited disease | — | 13 (81.2) | — | | Extended disease | — | 3 (18.8) | | I-IIIA | 44 (84.6) | — | | IIIB-IV | 8 (15.4) | — | | Recurrence | | | | | Yes | 18 (34.6) | 11 (68.7) | 0.0216 | | No | 34 (65.4) | 5 (31.3) | | Lymph node metastasis | | | | | Yes | 17 (32.7) | 2 (12.5) | 0.2012 | | No | 35 (67.3) | 14 (87.5) | | Other site metastases | | | | | Yes | 5 (9.6) | 2 (12.5) | 0.6640 | | No | 47 (90.4) | 14 (87.5) | | Grade of differentiation | | | | | Well/moderate | 32 (61.5) | 1 (6.2) | 0.0001 | | Poor/undifferentiated | 20 (38.5) | 15 (93.8) | | Degree of cell pleomorphism | | | | | Low | 25 (48.1) | 7 (43.7) | 0.7834 | | High | 27 (51.9) | 9 (56.3) | | Necrosis index | | | | | <50% | 38 (73.1) | 4 (25.0) | 0.0009 | | ≥50% | 14 (26.9) | 12 (75.0) | | Mitotic index | | | | | Low | 24 (46.2) | 0 (0) | 0.0006 | | High | 28 (53.8) | 16 (100) |
|
|
NSCLC, non-small cell lung carcinoma; SCLC, small cell lung carcinoma; %, percentages.
|
