Tissue Expression of Low and High Molecular Weight Cytokeratins in Lung Carcinoma Sections: Its Correlation with Some Clinic-Pathological Features

Table 2

Cytokeratins profile expression according to histopathological type.

Anti-CKs antibodies		34βE12^a		35BH11^b		MNF116^c
Low/high expression (%)		−	+	−	+	−	+
Epidermoid carcinoma	16	50.0	50.0	25.0	75.0	25.0	75.0
Adenocarcinoma	20	75.0	25.0	25.0	75.0	25.0	75.0
Large cell carcinoma	10	40.0	60.0	30.0	70.0	40.0	60.0
Others	6	50.0	50.0	50.0	50.0	40.0	60.0
Small cell carcinoma	16	0	0	56.3	43.7	56.3	43.7

^a34βE12 reacts with high molecular weight cytokeratins (1, 5, 10, and 14); ^b35BH11 stains cytokeratin 8 (low molecular weight cytokeratin); ^cMNF116 reacts with cytokeratins 5, 6, 8, 17, and probably also 19.