Tissue Expression of Low and High Molecular Weight Cytokeratins in Lung Carcinoma Sections: Its Correlation with Some Clinic-Pathological Features

Table 5

Survival of NSCLC patients according to antigens expression profile.

Antigens expression	34βE12^a		35BH11^b		MNF116^c		Ber-EP4^d
Low/high reactivity	−	+	−	+	−	+	−	+
Number of cases	41	11	26	26	24	28	29	23
% 4-year survival rate	87.8	27.3	73.1	76.9	66.7	82.1	82.8	65.2
Mean survival (months)	36.0	29.3	35.2	33.9	32.7	37.0	34.3	34.8
P value	0.0315		0.8380		0.1340		0.8268

^a34βE12 reacts with high molecular weight cytokeratins (1, 5, 10, and 14); ^b35BH11 stains cytokeratin 8 (low molecular weight cytokeratin); ^cMNF116 reacts with cytokeratins 5, 6, 8, 17, and probably also 19; ^dBer-EP4 antibody recognizes a transmembrane glycoprotein functioning as a cellular adhesion molecule.