Research Article

The Effect of Calcipotriol on the Expression of Human Defensin-2 and LL-37 in Cultured Human Keratinocytes

Figure 4

The expression of LL-37 mRNA in the keratinocytes was also upregulated when stimulated with LPS, TNF- 𝛼 , and UVB irradiation at 6, 12, and 24 hours. Similar to the hBD-2 results, LL-37 mRNA expression decreased after treatment with calcipotriol. *: Statistically significant between UV and CA + UV ( 𝑃 < . 0 1 ). # : Statistically significant between LPS and CA + LPS ( 𝑃 < . 0 1 ). + : Statistically significant between TNF-s and CA + TNF-a ( 𝑃 < . 0 1 ).
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