The SSX Family of Cancer-Testis Antigens as Target Proteins for Tumor Therapy

Figure 1

Protein homology and conserved domains among SSX orthologues. Shown is a sequence alignment of species-specific SSX protein sequences from canine, horse, human, macaque, chimpanzee, marmoset, mouse, and rat sources. Blue highlighting represents >75% sequence identity with consensus sequence shown on the bottom. The KRAB and SSXRD domain regions denoted by solid green bars are shown below the sequence alignment.