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Clinical and Developmental Immunology
Volume 2010 (2010), Article ID 170432, 13 pages
Current Hypotheses on How Microsatellite Instability Leads to Enhanced Survival of Lynch Syndrome Patients
1Department of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, NE 68178, USA
2Department of Pathology, Creighton University School of Medicine, Omaha, NE 68178, USA
3Department of Preventative Medicine, Creighton University School of Medicine, Omaha, NE 68178, USA
Received 8 January 2010; Accepted 13 April 2010
Academic Editor: C. Pauza
Copyright © 2010 Kristen M. Drescher et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citations to this Article [19 citations]
The following is the list of published articles that have cited the current article.
- Yvette Garbe, Ulrike Klier, and Michael Linnebacher, “Semiallogenic fusions of MSI+ tumor cells and activated B cells induce MSI- specific T cell responses,” Bmc Cancer, vol. 11, 2011.
- Kimberly D. Siegmund, Paul Marjoram, Simon Tavare, and Darryl Shibata, “High DNA Methylation Pattern Intratumoral Diversity Implies Weak Selection in Many Human Colorectal Cancers,” Plos One, vol. 6, no. 6, 2011.
- Sarah Popek, and Vassiliki L. Tsikitis, “Epidemiology of Inherited Colon Cancer,” Seminars in Colon and Rectal Surgery, vol. 22, no. 2, pp. 77–81, 2011.
- Frank A. Sinicrope, and Zhineng Jayson Yang, “Prognostic and predictive impact of DNA mismatch repair in the management o f colorectal cancer,” Future Oncology, vol. 7, no. 3, pp. 467–474, 2011.
- Yvette Garbe, Claudia Maletzki, and Michael Linnebacher, “An MSI Tumor Specific Frameshift Mutation in a Coding Microsatellite of MSH 3 Encodes for HLA-A0201-Restricted CD8(+) Cytotoxic T Cell Epitopes,” Plos One, vol. 6, no. 11, 2011.
- Cristina Bozzao, Alessandro Stella, and Patrizia Lastella, “Anticipation in Lynch Syndrome: Where We Are Where We Go,” Current Genomics, vol. 12, no. 7, pp. 451–465, 2011.
- Sha-Sha Guan, and Guang-Hai Dai, “Molecular biology and clinical features of hereditary non-polyposis colorectal cancer,” Acta Academiae Medicinae Sinicae, vol. 34, no. 3, pp. 293–297, 2012.
- D. Schiff, E. M. Lam, J. E. Parisi, C. Giannini, J. H. Uhm, B. M. Keegan, and O. H. Kantarci, “A 21-year-old woman with multiple cancers and a new brain lesion,” Neurology, vol. 78, no. 10, pp. 743–749, 2012.
- Noel F. C. C. de Miranda, Danny Goudkade, Ekaterina S. Jordanova, Carli M. J. Tops, Frederik J. Hes, Hans F. A. Vasen, Tom van Wezel, and Hans Morreau, “Infiltration of Lynch Colorectal Cancers by Activated Immune Cells Associat es with Early Staging of the Primary Tumor and Absence of Lymph Node Metast ases,” Clinical Cancer Research, vol. 18, no. 5, pp. 1237–1245, 2012.
- Jinru Shia, Hangjun Wang, Garrett M. Nash, and David S. Klimstra, “Lymph Node Staging in Colorectal Cancer: Revisiting the Benchmark of at Lea st 12 Lymph Nodes in R0 Resection,” Journal of The American College of Surgeons, vol. 214, no. 3, pp. 348–355, 2012.
- Jeong M. Bae, Nam-Yun Cho, Tae-You Kim, and Gyeong H. Kang, “Clinicopathologic and Molecular Characteristics of Synchronous Colorectal Cancers,” Diseases of the Colon & Rectum, vol. 55, no. 2, pp. 181–190, 2012.
- Amanda I. Phipps, John D. Potter, Polly A. Newcomb, Daniel D. Buchanan, Karen W. Makar, Andrea N. Burnett-Hartman, Anna E. Coghill, Michael N. Passarelli, John A. Baron, Dennis J. Ahnen, and Aung Ko Win, “BRAF mutation status and survival after colorectal cancer diagnosis according to patient and tumor characteristics,” Cancer Epidemiology Biomarkers and Prevention, vol. 21, no. 10, pp. 1792–1798, 2012.
- N. F. C. C. de Miranda, F. J. Hes, T. van Wezel, and H. Morreau, “Role of the microenvironment in the tumourigenesis of microsatellite unstable and MUTYH-associated polyposis colorectal cancers,” Mutagenesis, vol. 27, no. 2, pp. 247–253, 2012.
- Justyna Klusek, Stanislaw Gluszek, and Jolanta Klusek, “Selected mutations with high risk of colorectal cancer,” Przeglad Gastroenterologiczny, vol. 7, no. 1, pp. 1–6, 2012.
- Matthias Kloor, Laura Staffa, Aysel Ahadova, and Magnus Knebel Doeberitz, “Clinical significance of microsatellite instability in colorectal cancer,” Langenbeck's Archives of Surgery, 2013.
- Pilar Garre, Lorena Martín, Inmaculada Bando, Alicia Tosar, Patricia Llovet, Julián Sanz, Atocha Romero, Miguel Hoya, Eduardo Díaz-Rubio, and Trinidad Caldés, “Cancer risk and overall survival in mismatch repair proficient hereditary non-polyposis colorectal cancer, Lynch syndrome and sporadic colorectal cancer,” Familial Cancer, 2013.
- Guillermo Aldave, Eva Pay, Francisco Queipo, Miguel Angel Idoate, and Jorge Guridi, “Metástasis de un adenocarcinoma prostático en tronco cerebral en el contexto de un síndrome de Muir-Torre,” Neurocirugía, vol. 24, no. 2, pp. 78–81, 2013.
- Paul J Barrow, Tara Clancy, and D Gareth Evans, “Key genetic considerations in the management of suspected hereditary colorectal cancer,” Colorectal Cancer, vol. 2, no. 1, pp. 31–41, 2013.
- Linghua Wang, and David A. Wheeler, “Genomic Sequencing for Cancer Diagnosis and Therapy,” Annual Review of Medicine, vol. 65, no. 1, pp. 33–48, 2014.