Research Article
Cytokine Production by Peripheral Blood CD4+ and CD8+ T Cells in Atopic Childhood Asthma
Table 4
Percentage of CD4+ T cells and CD8+ T cells producing IL-2, IL-4, IL-10, IL-13, INF-γ, and TNF-α before and after in vitro activation with phorbol 12-myristate-13-acetate and ionomycin in the four groups of asthmatics (1-intermittent, 2-mild persistent, 3-moderate persistent, and 4-severe persistent asthma). In parenthesis, the frequencies of spontaneous cytokine staining (in the presence of monensin alone) are presented.
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severe persistent asthma versus intermittent asthma. severe persistent asthma versus moderate persistent asthma. -values from Mann-Whitney U-test. Data as shown as mean ± SE. |