Immune Response in Ovarian Cancer: How Is the Immune System Involved in Prognosis and Therapy: Potential for Treatment Utilization

<table>VEGF exerts its signalling effect via its receptor VEGFR. VEGF, mainly the VGEFA isoform exerts its effects via binding its receptor VEGFR (mainly VEGFR2). It is a powerful angiogenic factor that holds a pivotal role in tumor progress and metastasis. It comprises an attractive target for possible agents that will block its function and therefore enhance patients’ survival. ID: Intracellular domain, ED: extracellular domain, TD: Transmembrane domain.</table>

Journal of Immunology Research

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Figure 1: Immune Response in Ovarian Cancer: How Is the Immune System Involved in Prognosis and Therapy: Potential for Treatment Utilization 