Potential Target Antigens for a Universal Vaccine in Epithelial Ovarian Cancer

Table 3

Expression levels of antigen and MHC class I components.

	P53^1	SP17^1	Survivin^1	WT1^1	NY-ESO-1^1
	n (%)	n (%)	n (%)	n (%)	n (%)
Normal/negative	130 (52.0)	78 (31.1)	23 (10.0)	100 (43.7)	219 (89.0)
Overexpression/positive	120 (48.0)	173 (68.9)	208 (90.0)	129 (56.3)	27 (11.0)
Missing	20	19	39	41	24
	HLA- A^+/ 𝛽2- m^+2	HLA-B/ C^+/ 𝛽2- m^+2	MHC class I^3
Positive^4	98 (53.6)	136 (74.7)	143 (78.1)
Negative^4	85 (46.4)	46 (25.3)	40 (21.9)
Missing		1

𝟏primary EOC patients, n = 270; 2staining in subgroup, n = 183; 3MHC class I expression is defined as HLA-A and 𝛽₂-m and/or HLA-B/C and 𝛽₂-m coexpression; 4positive is both components HLA-A/B/C and 𝛽₂-m expressed, negative are all other phenotypes.