Development of Type 1 Diabetes Mellitus in Nonobese Diabetic Mice Follows Changes in Thymocyte and Peripheral T Lymphocyte Transcriptional Activity

<table>Confirmation of microarray data by qRT-PCR. The Fasl, Tlr3, and Tlr4 genes were downregulated in thymocytes from prediabetic animals, Foxp3 was upregulated in peripheral CD3<sup>+</sup> lymphocytes from diabetic animals, and Themis was upregulated in thymocytes from prediabetic animals.</table>

Journal of Immunology Research

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Figure 4: Development of Type 1 Diabetes Mellitus in Nonobese Diabetic Mice Follows Changes in Thymocyte and Peripheral T Lymphocyte Transcriptional Activity 

Figure 4 | Development of Type 1 Diabetes Mellitus in Nonobese Diabetic Mice Follows Changes in Thymocyte and Peripheral T Lymphocyte Transcriptional Activity 