Immune Microenvironment in Colorectal Cancer: A New Hallmark to Change Old Paradigms

Figure 2

Early Apoptotic Phase: Calreticulin (CRT). oxaliplatin induces translocation of the intracytoplasmic protein calreticulin to the cell surface, inducing the apoptotic cell antigen presentation to dendritic cells and stimulating specific antitumor T-cell responses.