The Desmoplastic Stroma Plays an Essential Role in the Accumulation and Modulation of Infiltrated Immune Cells in Pancreatic Adenocarcinoma

Figure 4

Elevated gene expression levels of markers of infiltrating immune cells in PDAC tissue. RNA was obtained from PDAC (𝑛=30) and normal pancreatic tissue samples (𝑛=10) and assessed for relative gene expression levels of markers expressed by (a and b) macrophages (CD68 and CD163), (c and d) myeloid dendritic cells (CD1a and CD1c), (e) plasmacytoid dendritic cells (CD303), and (f–h) DC maturation/activation status markers (CD83, CD208 and CD209). *𝑃<0.05, **𝑃<0.05, ***𝑃<0.001.

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