Current Immunotherapeutic Approaches in Pancreatic Cancer

Figure 5

Combination therapies of immunotherapy and standard radio- and chemotherapy. Currently applied standard therapies such as radio- and chemotherapy target bulk cancer cells that are less resistant than cancer stem cells. This leads to initial regression of the tumor mass but eventually regrowth from residual CSCs. Combined therapies of standard therapies and immunotherapeutic approach targeting CSCs would cut off the rejuvenating supply of CSCs and resulted in tumor eradication.