Patients with Multiple Myeloma Develop SOX2-Specific Autoantibodies after Allogeneic Stem Cell Transplantation
Figure 2
(a) Analysis of SOX2-specific IgG antibody responses in MM patients () and in healthy donors (). Results are shown as optical density (OD) at 405 nm. Horizontal bar represents the cut-off value for positivity (OD > 0.274). (b) Analysis of influenza-nucleoprotein- (FLU-), tetanus-toxoid- (TT-) and glutathione-S-transferase- (GST-) specific antibody responses in the same collective of MM patients and healthy donors. (c) Incidence of SOX2-specific antibody responses in the group of MM patients compared with the group of healthy donors (7.7% versus 2.0%). We found significantly more individuals with SOX2-specific antibody responses in the MM group than in the healthy donor group ().
