Anti-IL-6 Receptor Antibody Causes Less Promotion of Tuberculosis Infection than Anti-TNF- Antibody in Mice
Figure 7
Cytokine production of PPD-stimulated spleen cells from IL-6 KO, TNFR1 KO, TNFR1 and IL-6 DKO, and WT BALB/C mice. Single cell suspensions obtained from each group 4 weeks after infection in IL-6 KO mice (), TNFR1 KO mice (), and WT DBA/1 control mice () were pooled and cultured with 20ā€‰g/mL of PPD for 48ā€‰h, and then cytokine concentrations were measured. Results are means Ā± S.E.M. of triplicate cultures in each group. * by Studentā€™s -test.